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Conformational Study of Decamer DNA Duplex d(ACGTATACGT)2 by NMR Spectroscopy
Joon-Hwa Lee, Jin-Young Park, Hi-Jung Han, and Byong-Seok ChoiJ. Kor. Magn. Reson. Soc. 1, 6370 (1997)
The conformation of the self-complementary decamer duplex, d(ACGTATACGT)2 (TATA-duplex) has been studied dy proton NMR spectroscopy. The duplex is essentially B-type, with distortions apparent at the TATA steps. These conformational distortion which may be preferable to occur in the thymine residue on the 5'-side, has been investigated by unusual NOE crosspeaks.
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