@article{Han13a, author={Huijong Han and Petri Kursula}, title={Preliminary crystallographic analysis of the {N}-terminal {PDZ}-like domain of periaxin, an abundant peripheral nerve protein linked to human neuropathies}, journal={Acta Cryst. F}, volume={69}, pages={804--808}, year={2013}, keywords={myelin; periaxin; PDZ-like domain; neuropathy;}, url={https://doi.org/10.1107/S1744309113016266}, doi={10.1107/S1744309113016266}, abstract={Periaxin (PRX) is an abundant protein in peripheral nerves and contains a predicted PDZ-like domain at its N-terminus. The large isoform, L-PRX, is required for the maintenance of myelin in the peripheral nervous system and its defects cause neurological disease. Here, the human periaxin PDZ-like domain was crystallized and X-ray diffraction data were collected to 2.85 \AA resolution using synchrotron radiation. The crystal belonged to the primitive hexagonal space group $P$3$_1$21$ or $P$3$_2$21, with unit-cell parameters $a$ = $b$ = 80.6, $c$ = 81.0 \AA, $\gamma$ = 120$\deg$ and either two or three molecules in the asymmetric unit. The structure of PRX will shed light on its poorly characterized function in the nervous system.}
}