상길! 홈페이지 상길이를 만나요| ZanNavi's space
  현재위치 ► ZanNavi's space : iBib : Abstract  

----------------------------------------------------------------------
iBib | list | admin

Abstract of [Han13]

[Han13]
No PDF available

Myelin-specific proteins: a structurally diverse group of membrane-interacting molecules

Huijong Han, Matti Myllykoski, Salla Ruskamo, Chaozhan Wang, and Petri Kursula

BioFactors 39, 233–241 (2013)

[bib][BibTeX][link]doi:10.1002/biof.1076

The myelin sheath is a multilayered membrane in the nervous system, which has unique biochemical properties. Myelin carries a set of specific high-abundance proteins, the structure and function of which are still poorly understood. The proteins of the myelin sheath are involved in a number of neurological diseases, including autoimmune diseases and inherited neuropathies. In this review, we briefly discuss the structural properties and functions of selected myelin-specific proteins (P0, myelin oligodendrocyte glycoprotein, myelin-associated glycoprotein, myelin basic protein, myelin-associated oligodendrocytic basic protein, P2, proteolipid protein, peripheral myelin protein of 22 kDa, 2',3'-cyclic nucleotide 3'-phosphodiesterase, and periaxin); such properties include, for example, interactions with lipid bilayers and the presence of large intrinsically disordered regions in some myelin proteins. A detailed understanding of myelin protein structure and function at the molecular level will be required to fully grasp their physiological roles in the myelin sheath.

Tags: myelin, protein structure, membrane protein, intrinsic disorder, CSSB-HZI, DESY, review


made by ZN

----------------------------------------------------------------------

이 페이지의 최종수정일: 2021.2.2
Copyright (C) 2000-2024 손상길
저작권에 대한 본 사항이 명시되는 한, 어떠한 정보 매체에 의한 본문의 전재나 발췌도 무상으로 허용됩니다. [copyleft]